3rd International Toxicology Conclave, a two day long Industries-Academia meet has been inaugurated in the SH Zaidi Auditorium of CSIR-Indian Institute of Toxicology Research, Lucknow on November 5, 2017. The inaugural address for the program was delivered by the Chief Guest of the day, Dr Rakesh Kumar, Director, CSIR-National Environmental Engineering Research Institute, Nagpur, India, followed by the keynote address by Dr B. Sesikeran, Former Director, National Institute of Nutrition, Hyderabad, India on the topic “Safety assessment for nutrients”. He emphasized on the adequate balance of micro and macro nutrients in our daily life and how both over and under consumption of the vitamins and other nutrients may significantly affect the human health.
On day one, the scientific program was comprised of two technical sessions; each one was followed by an expert panel discussion on the theme of the session and one scientific poster session. Session I was emphasized on the theme ‘Environmental Monitoring & Risk Assessment’ consisting of 5 lectures followed by a panel discussion by the experts of the area.
Dr SC Barman, Senior Principal Scientist of CSIR-Indian Institute of Toxicology Research (CSIR-IITR), Lucknow appraised about the health issues associated with the indoor and outdoor air quality and the efforts made by CSIR-IITR to assess the pollutant load in the air, its impact on human health and mitigation measures being taken to address the issues. In the illustrative talk, Dr. Satish Sohoni of Hikal Limited, Mumbai, stressed upon the ways by which his firm is working to increase the level of groundwater. He detailed about the company mission and efforts made by so far by Smaart Water, an integral company for Water Solutions Management in Mumbai, to provide an integrated and holistic water solution for a lifetime. Dr. Dinesh Mohan of Jawaharlal Nehru University, Delhi discussed his research work carried out to address the issue of environmental pollution by burning of crop biomass in the agriculture fields. He has developed low cost green adsorbent bio-charcoal from plant waste material which has high organic carbon contents and resistant to decomposition. This biochar will not only be immensely helpful to solve the crop burning issues but also be considered as an environmentally sustainable technology for water, soil and climate change mitigation. He further added that the crop residue may be converted into biofuel, heat and power using different thermal, biochemical and mechanical platforms. Dr. Mukesh Sharma of IIT, Kanpur, deliberated regarding the uncertainties in a physiologically based pharmacokinetic model which explains regarding the uptake, accumulation, estimation and elimination of lead in the human body. He narrated about the applicability of this model to estimate the human health risk of the xenobiotic exposure. Dr. John Colbourne, Professor and Chair of Environmental Genomics, University of Birmingham, United Kingdom, addressed the issues associated with the interpretation of the data due to the complexity of genome-environment interaction. He highlighted the importance of Daphnia and Fundulus as model species to point-out the importance of measuring the elements of the genome that may be targeted towards the natural selection resulting in increased tolerance to the exposure of toxic environmental conditions. His findings reveal chemical modes of action leading to harm to animals including humans. There was a panel of experts to discuss the highlights of the session to reach any firm conclusion out of deliberations and making the final recommendations for implementation.
The session-II themed on ‘Innovations and Translational Research’ was having four lectures followed by an expert panel discussion. Dr. Anil Wali of Foundation for Innovation and Technology Transfer New Delhi emphasized upon the bridging the gaps between academia and industry to synchronize the research, innovation and start-ups in India. The talk of Dr. R Govindarajan of Zydus Wellness Limited, Ahmedabad, focused on the global revival plant-based traditional medicines. He appraised about the developments coming up in the research parameters on quality control of herbal medicines. He also emphasized on the need of scientific validation of data generated for developed herbal medicines. Dr. H Purushotham of National Research Development Cooperation, New Delhi has delivered a talk focusing on the identification of the critical factors for successful technology transfer in the Indian scenario. His studies identify the critical factors influencing successful technology transfer from Indian public funded R&D institutions to the industry. Dr. Arun Chandru of Pandrum Technologies, Bangaluru, India has discussed the role of bioengineered 3D functional human tissue and organoids as a possible vital tool to bridge the gap between traditional 2D cell culture assay, animal models and human trials in the development of new drugs and vaccines. Following the session lectures panel of experts discussed the issues highlighted during the presentations and formulated the final recommendations for the possible implementations.