Scientific Staff

Dr. Rajnish Kumar Chaturvedi
Senior Scientist
Developmental Toxicology
CSIR-Indian Institute of Toxicology Research
Vishvigyan Bhavan, 31, Mahatma Gandhi Marg,
Lucknow - 226 001. Uttar Pradesh, India
Email: rajnish[at]iitr[dot]res[dot]in | Alternate Email: itrcrajnish@gmail.com
Tel: 522-2613786 | Extension: 0522-2217655
Fax: 522-2628227
Area of Specialization
Biochemical and Molecular Neurotoxicology, Neural Stem Cell Biology, Regenerative medicine and neurodegenerative disorders, Cellular and Molecular Mechanism of Parkinson and Huntington Disease
Current R&D/S&T Activities

  • Normal brain development also referred as neurogenesis, involves a balance between Neural Stem Cell (NSC) proliferation, their migration to different parts of the brain followed by differentiation to neurons,     astrocytes and oligodendrocytes. For optimum brain development newly generated neurons move along precise pathways from their points of origin to their assigned locations, establish synapses with each other, and communicate via these synapses. Several environmental toxicants are reported to cause developmental neurotoxicity in both children and adults. We are trying to understand how environmental toxicants (pesticides and xenoestrogen) affect key events of neurogenesis including regulatory cell signaling pathways. Further, we are involved to assess the molecular and/or cellular events that are target(s) for inhibition of neurogenesis.
  • Use of human and rodent Neural Stem Cells as an alternate in vitro model to assess the neurotoxic potential of environmental contaminants.
  • To assess the cellular and molecular mechanism of neurodegenerative disorders specially Parkinson’s disease, and how environmental toxicants modulate the disease pathogenesis.
  • Identification of novel molecular therapeutic targets in neurodegenerative disorders.
  • Identification of molecules which can induce "BRAIN SELF REPAIR" by actviating resident Neural Stem Cell Population.

Awards/Honours/ Distinctions

OPPI-Young Scientist Award-2016 in the field of Pharmaceutical Biotechnology/Nanotechnology.

Shri Om Prakash Sharma Young Scientist Award in Biomedical Research-2016

NASI-Scopus Young Scientist Award-2015 in the field of Medicine.

Lady Tata Memorial Young Scientist Award-2014, in the field of Biological Sciences.

National Academy of Sciences of India (NASI) Young Scientist Platinum Jubilee Award-2013, in the field of Biomedical, Molecular Biology and Biotechnology

The Indian National Science Academy (INSA) Young Scientists-2012 for Health Sciences

Gauri Ganguly Memorial Young Scientist Award-2012 of Indian Science Congress Association (ISCA), Kolkata.

U.P. Council of Science and Technology "Young Scientist Award" for the year 2005-2006.

1st prize in "Parkinsons Disease Quiz Contest" organized by Novartis Pharma during International Congress on Parkinsons disease and Related Disorders, at Berlin Germany, 2005.

Best paper award during 2nd Federation of Asian-Oceanic Neuroscience Societies (FAONS) Symposium at Tehran, Iran, 2004.

Best paper award during International conference on Theoretical Neurobiology organized by National Brain Research Centre, New Delhi, 2003.

Best paper award during INDO-US colloquium on Brain Research at New Delhi, 2002.


Memberships of professional societies:


Society for Neuroscience (SFN)-USA

New York Academy of Sciences (NYAS)-USA

International Society of Neurochemistry (ISN)

International Neurotoxicology association (INA)

International Brain Research Organization (IBRO)

Indian Academy of Neurosciences (IAN)

Asian Pacific Society of Neurochemistry (APSN)

Member of reviewers database of Nutritional Neuroscience, Progress in Neuro-psychopharmacology and Biological Psychiatry, Neurodegeneration and Neuroscience Letters

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